The laugh track after Screech peeked his head out from the locker was what made it for me. The editors clearly didn't realize what was happening, and just had the immediate reaction of "Oh, the jew kid is saying something! Hit the red button!"
"Don't Do Drugs" had a decent start in the ratings, but nosedived when ABC moved "MacGuyver" to the same timeslot, much to the dismay of series star Corey Feldman. A follow up series "Okay, Do Drugs Then." was even less successful, perhaps due to the fact that the title was sarcastic and the entire series consisted of Wilford Brimley giving the viewer a series of stern looks.